While several top seeds will have their say, a look at some emerging players who could be serious contenders.
Jannik Sinner secured the year-end world number one ranking by beating Czech 30th seed Tomas Machac in the Shanghai Masters semi-finals.
Italian Bracciali banned for life, Starace for 10 years
Sumit Nagal staged a grand recovery to get the better of Jason Jung of Chinese Taipei 3-6, 6-2, 6-0 and book his place in the quarter-finals of the Chennai Open ATP Challenger in Chennai on Thursday.
Rohan Bopanna's and Aisam-ul-Haq Qureshi's wait for their first ATP title continued after they lost the final of the Pilot Pen Tennis tournament to Wimbledon finalists Robert Lindstedt and Horia Tecau in New Haven, USA.
Jack Sock ended local favourite Julien Benneteau's run at the Paris Masters with a 7-5, 6-2 victory to reach the final and move to the brink of an ATP Finals spot on Saturday.
The seventh seed Indian overcame stiff resistance from American Daniel Nguyen before prevailing 7-5, 4-6, 7-6(5) in the rain-hit final that lasted three hours and 31 minutes, turning out to be the longest summit clash in the ATP Challenger Tour history.
Djokovic looked in fine nick in Shanghai, playing with consistency throughout the tournament to reach his fifth final at the ATP Masters 1000 event
American qualifier Steve Johnson is through to his first ATP Tour semi-final after an emphatic victory at the Delray Beach Open on Friday.
The unanswerable question, of course, is whether Djokovic is the GOAT. That's a complex issue over which fans will forever bicker, observes Kanika Datta.
Russian Daniil Medvedev's 2022 season opened with a stunning defeat at the hands of Frenchman Ugo Humbert after a three-hour dogfight in a steamy Ken Rosewall Arena at the ATP Cup on Sunday.
Russia's Andrey Rublev overcame Grigor Dimitrov 7-6(7), 6-3 in their semi-final clash at the Shanghai Masters on Saturday, and will now face Hubert Hurkacz, who beat Sebastian Korda.
The Indo-Pakistan tennis duo of Rohan Bopanna and Aisam-ul-Haq Qureshi has booked a berth in the season-ending ATP World Tour Finals to be held from November 20 to 27 at London's O2 arena.
Casper Ruud gained sweet revenge over Stefanos Tsitsipas as he beat the Greek fifth seed 7-5, 6-3 to win the Barcelona Open on Sunday.
Both scored contrasting semi-final victories on Saturday.
World number one Novak Djokovic will bid for a record fourth successive ATP World Tour Finals crown in London later this year after becoming the first man to qualify for the season-ender.
The Indian has won five ATP Masters 1000 titles with five different partners, although he has never won a major championship in men's doubles. Not bad for someone whose knees lack cartilage.
Alcaraz will hope to bury memories of an injury-plagued start to last year when he missed the Australian Open
World No 1 Rafael Nadal is confident that arch-rival Roger Federer will be able to accumulate the points needed over the next few weeks to seal his spot for the season-ending ATP finale in London.
World No 1 Rafael Nadal, who is hoping to recover from a knee injury to play in the season-ending showpiece, heads the other group and will face Belgian David Goffin, Bulgarian debutant Grigor Dimitrov and Austrian Dominic Thiem.
Sumit Nagal won the Heilbronner Neckarcup ATP Challenger event beating Alexander Ritschard of Switzerland
Nagal is coming off a title triumph during the Heilbronn Challenger last week, which happens to be his second Challenger title this season after the Chennai Challenger in February.
Roger Federer's decision to withdraw means Switzerland can no longer take part in the nation-based event on January 3-12
After registering a runner-up finish in the Qatar Open, Andy Murray set himself a target of registering 800 career wins.
French Open and Wimbledon champion Alcaraz, who won both of his previous meetings with Sinner this year, recovered from a slow start to wrap up victory in three hours, 21 minutes and improve his head-to-head record with the Italian to 6-4.
World No. 2 Carlos Alcaraz defeated Tsitsipas in the 2021 US Open and in last year's Miami Masters and Barcelona Open.
French Open champion Stan Wawrinka has become the fourth player to qualify for the season-ending ATP World Tour Finals in London.
One thing is beyond doubt after eight fabulous days of action at the ATP World Tour Finals -- tennis has found a spectacular new venue at London's space-age O2 Arena.
The Spaniard bore little resemblance to the player who once terrorised his opponents as he slumped to a 6-1, 7-6 defeat by Russia's Nikolay Davydenko.
Rohan Bopanna and Sumit Nagal have secured their Paris Olympics 2024 quotas for India
Nadal was much more than a claycourt bully, though. He spent more than 900 successive weeks from 2005 in the ATP's top 10, 209 of them at number one and at the age of 24 became the youngest player to complete the career Grand Slam.
Tallon Griekspoor prevailed in a high-voltage three-set final against Benjamin Bonzi to win his maiden ATP World Tour title.
Home favourite Kei Nishikori defeated Frenchman Richard Gasquet 7-6(2), 6-1 in the semi-finals of the Japan Open on Saturday, setting up a final against Russian qualifier Daniil Medvedev.
Novak Djokovic was seriously rattled early on by inspired American teenager Nishesh Basavareddy but rallied for a 4-6, 6-3, 6-4, 6-2 victory on Monday.
World number one Novak Djokovic saw off Canadian Denis Shapovalov 6-3, 6-4 to win his fifth Paris Masters title on Sunday in a warning to his rivals ahead of the ATP Finals, while Ashleigh Barty finished the season in style by beating defending champion Elina Svitolina 6-4, 6-3 to add the WTA Finals title to her end-of-year world number one rank.ing
American Jack Sock clinched the last spot in the ATP Tour finals when he beat Serbian qualifier 5-7, 6-4, 6-1 to win the Paris Masters title on Sunday.
A final decision is expected by March based on the hosting and COVID-19 contingency proposals received from bidders.
Photos from the ATP World Tour Finals matches played in London on Monday
Novak Djokovic has reportedly proposed to move the ATP World Tours Finals from London after 2015 by citing the need to expose the tournament to more cities around the world.
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